Shi Y, Li Y, Wang Y, Zhuang J, Wang H, Hu M, Mo X, Yue S, Chen Y, Fan X, Chen J, Cai W, Zhu X, Wan Y, Zhong Y, Ye X, Li F, Zhou Z, Dai G, Luo R, Ocorr K, Jiang Z, Li X, Zhu P, Wu X, Yuan W. The Functional Polymorphism R129W in the BVES Gene Is Associated with Sporadic Tetralogy of Fallot in the Han Chinese Population. Genet Test Mol Biomarkers. 2019 Aug 6. doi: 10.1089/gtmb.2019.0085. [Epub ahead of print] PMID:31386585
Walls SM, Cammarato A, Chatfield DA, Ocorr K, Harris GL, Bodmer R. Ceramide-Protein Interactions Modulate Ceramide-Associated Lipotoxic Cardiomyopathy. Cell Rep. 2018 Mar 6;22(10):2702-2715. doi: 10.1016/j.celrep.2018.02.034. PMID:29514098
Zeng Q, Wan Y, Zhu P, Zhao M, Jiang F, Chen J, Tang M, Zhu X, Li Y, Zha H, Wang Y, Hu M, Mo X, Zhang Y, Chen Y, Chen Y, Ye X, Bodmer R, Ocorr K, Jiang Z, Zhuang J, Yuan W, Wu X. The bHLH Protein Nulp1 is Essential for Femur Development Via Acting as a Cofactor in Wnt Signaling in Drosophila.Curr Mol Med. 2018 Mar 9;17(7):509-517. doi: 10.2174/1566524018666180212145714. PMID:29437009
Ivy JR, Drechsler M, Catterson J, Bodmer R, Ocorr K, Paululat A., Hartley PS Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes. PLoS One. 2015 Aug 24;10(8):e0134620. doi: 10.1371/journal.pone.0134620. eCollection 2015 PMID:26301956
Zarndt R, Piloto S, Powell F, Haddad G, Bodmer R*, Ocorr K* Cardiac responses to hypoxia and reoxygenation in Drosophila. Am J Physiol Regul Integr Comp Physiol. 2015 Sep 16:ajpregu.00164.2015. doi: 10.1152/ajpregu.00164.2015. [Epub ahead of print] PMID:26377557 *Co-corresponding Authors
Kaushik G, Spenlehauer A, Sessions AO, Trujillo AS, FuhrmannA, Fu Z, Venkatraman V, Pohl D, Tuler J, Wang M, Lakatta EG, Ocorr K, Bodmer R, Bernstein SI, Van Eyk JE, Cammarato A, Engler AJ. Vinculin-network mediated cytoskeletal remodeling and regulation of contractile function in aging myocardium SciTranslMed. 2015 Jun17;7(292):292ra99. doi:10.1126/scitranslmed.aaa5843. PMID:26084806
Martinez-Morentin L, Martinez L, Piloto S, Yang H, Schon E, Garesse R, Bodmer R, Ocorr K*, Cervera M*, Arredondo J*. Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model. Hum Mol Genet.. 2015 Mar 19. pii: ddv106. [Epub ahead of print] PMID:25792727 *Co-corresponding authors
Diop S, Bisharat-Kernizan J, Birse R, Oldham S, Ocorr K, Bodmer R. PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase. Cell Reports . 2015 S2211-1247(15)00168-0. doi: 10.1016/j.celrep.2015.02.022. PMID:25753422
Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, and Yuan J X-L. Notch Activation of Ca2+ Signaling Mediates Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. Am. J Resp. Cell Mol. Biol. 2015 PMID:25569851
Cammarato A, Ocorr S, Ocorr K. Enhanced assessment of contractile dynamics in Drosophila hearts. BioTechniques. 2015 58(2):77-80. doi: 10.2144/000114255. PMID:25652030
Lim H-Y, Wang W, Chen J, Ocorr K, Bodmer R. ROS Regulate Cardiac Function via a Distinct Paracrine Mechanism. Cell Reports. 2014 7, 35–44.
Nishimura M, Kumsta C, Kaushik G, Ding Y,Bisharat-Kernizan J,Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, and Ocorr K. Dual Role of Integrin and Integrin-Linked Kinase in Cardiac Aging and Integrity. Aging Cell. 2014 13, 431-40.
Tang M, Yuan W, Bodmer R, Wu X, Ocorr K. The role of pygopus in the differentiation of intra-cardiac valves in Drosophila. Genesis. 2014 Jan;52(1):19-28. PMID:24265259.
Melkani GC, Trujillo AS, Ramos R, Bodmer R, Bernstein SI, Ocorr K. Huntington's Disease Induced Cardiac Amyloidosis Is Reversed by Modulating Protein Folding and Oxidative Stress Pathways in the Drosophila Heart. PLoS Genet. 2013 9(12): :e1004024 PMID:24367279. (Cover Image; Image of the Week in The Scientist)
Tang M, Yuan W, Bodmer R, Ocorr K*, Wu X*. Pygopus Maintains Drosophila Heart Function with Age Independently of Canonical Wnt Signaling. Circ Cardiovasc Genet. 2013 6(5):472-80 PMID:24046329. *Co-corresponding authors
Wang X, Liao P, Fan X, Wan Y, Wang Y, Li Y, Jiang Z, Ye X, Mo X, Ocorr K, Deng Y, Wu X. Yuan W. CXXC5 Associates with Smads to Mediate TNF. Current Molecular Medicine. 2013 13:1385-1396 PMID: 23906331
Zhang R, Han P, Yang H, Ouyang K, Lee D, Lin YF, Ocorr K, Kang G, Chen J, Stainier DY, Yelon D, Chi NC. In vivo cardiac reprogramming contributes to zebrafish heart regeneration. Nature. 2013 Jun 27;498(7455):497-501. doi: 10.1038/nature12322. Epub 2013 Jun 19.
Harpaz N, Ordan E, Ocorr K, Bodmer R, Volk T. Multiplexin Promotes Heart but Not Aorta Morphogenesis by Polarized Enhancement of Slit/Robo Activity at the Heart Lumen. PLoS Genet. 2013 Jun;9(6):e1003597. PMID:23825967.
Zhang Z, Hsieh B, Poe A, Anderson J, Ocorr K, Gibson G, Bodmer R. Complex Genetic Architecture of Cardiac Disease in a Wild Type Inbred Strain of Drosophila melanogaster. PLoS One. 2013 Apr 29;8(4):e62909. PMID:23638165.
Na J, Musselman LP, Pendse J, Baranski TJ, Bodmer R, Ocorr K*, Cagan R. A Drosophila Model of High Sugar Diet-Induced Cardiomyopathy. PLoS Genet. 2013 9(1):e1003175. PMID:23326243. *Corresponding author (Cover Image)
Spindler SR, Li R, Dhahbi JM, Yamakawa A, Mote P, Bodmer R, Ocorr K, Williams R, Wang Y, & Ablao KP. Statin treatment increases lifespan and improves cardiac health in Drosophila. PLoS One. 2012;7(6):e39581 PMID: 22737247.
Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012;9(5):812-20. Epub 2011 Dec 2.
Grossman T, Gamliel A, Wessells RJ, Taghli-Lamallem O, Jepsen K, Ocorr K, Korenberg J, Kirk L. Peterson KL, Rosenfeld MG, Bodmer R, Bier E. Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects. PloS Genetics 2011 11:e100234 PMID:22072978.
Nishimura M, Ocorr K, Bodmer R, Cartry J. Drosophila as a model to study cardiac aging. Exp. Gerontology. 2011 46: 326-30. PMID:21130861.
Melkani G, Bodmer R, Ocorr K* and Bernstein SI*. The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model. PLoS One. 2011;6(7):e22579. PMID: 21799905. *Co-corresponding authors
Eleftherianos I, Won S, Chtarbanova S, Squiban B, Ocorr K, Bodmer R, Beutler B, Hoffmann A and Imler J-L. KATP channel-dependent regulation of cardiotropic viral infections. Proc Natl Acad Sci USA. 2011 108(29):12024-9. PMID:21719711.
Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol. 2011 193(7):1181-96. PMID:21690310.
Lim HY, Wang W, Wessells RJ, Ocorr K, Bodmer R. Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila. Genes Dev. 2011 25(2):189-200. PMID:21245170.
Fan X, Yang Q, Wang Y, Zhang Y, Wang J, Yuan J, Li Y, Wang Y, Deng Y, Yuan W, Mo X, Wan Y, Ocorr K, Yang X, Wu X. Cloning and characterization of the cardiac-specific Lrrc10 promoter. BMB Rep. 2011;44(2):123-8.
Luo N, Li G, Li Y, Fan X, Wang Y, Ye X, Mo X, Zhou J, Yuan W, Tan M, Xie H, Ocorr K, Bodmer R, Deng Y, Wu X. SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity. BMB Rep. 2010 43(5):355-61. PMID:20510020.
Hu J, Yuan W, Tang M, Wang Y, Fan X, Mo X, Li Y, Ying Z, Wan Y, Ocorr K, Bodmer R, Deng Y, Wu X. KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1. BMB Rep. 2010 43(1):17-22. PMID:20132730.
Birse RT, Choi J, Reardon K, Rodriguez J, Graham S, Diop S, Ocorr K, Bodmer R, Oldham S. High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila. Cell Metab. 2010 12(5):533-44. PMID: 21035763.
Huang W, Deng Y, Dong W, Yuan W, Wan Y, Mo X, Li Y, Wang Z, Wang Y, Ocorr K, Zhang B, Lin S, Wu X. The effect of excess expression of GFP in a novel heart-specific green fluorescence zebrafish regulated by nppa enhancer at early embryonic development. Mol Bio Rep. 2011;38(2):793-9. Epub 2010 Apr 10.
Lee JH, Budanov AV, Park EJ, Birse R, Kim TE, Perkins GA, Ocorr K, Mark H. Ellisman, Bodmer R, Bier E, Karin M. Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies. Science. 2010 327(5970):1223-8. PMID: 20203043.
Neely GG, Kuba K, Cammarato A, Isobe K, Amann S, Zhang L, Murata M, Elmén L, Gupta V, Arora S, Sarangi R, Dan D, Fujisawa S, Usami T, Xia C, Keene AC, Alayari NN, Yamakawa H, Elling U, Berger C, Novatchkova M, Koglgruber R, Fukuda K, Nishina H, Isobe M, Pospisilik JA, Imai Y, Pfeufer A, Hicks AA, Pramstaller PP, Subramaniam S, Kimura A, Ocorr K, Bodmer R, Penninger JM. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell. 2010 141:142-53. PMID:20371351.